A guide to the MonaLisa Touch treatment

MonaLisa Touch™ is a vaginal rejuvenation treatment (not to be confused with aesthetic treatments) based on a special CO2 fractional laser, specifically created for this particular application.


Issues of vaginal health are commonly seen in post-menopausal women, breast cancer survivors and women who have had a hysterectomy. In the US, there are nearly 46M women between the ages of 50 and 80,* and over 2.8M breast cancer survivors**.

* US Census, 2010 ** National Institutes of Health 2011

The following histological images show the vaginal mucosa before and after the MonaLisa Touch treatment. The marked change to the epithelium post-treatment is clearly illustrated.

Histological preparation of a section of the vaginal mucosa stained with haematoxylin and eosin (H&E). (A) Vaginal mucosa in the basal condition with a thinner epithelium. (B) The same patient 2 months after a session with the MonaLisa Touch®. The thicker epithelium and shedding of numerous big cells from the free surface, together with the larger diameter of epithelial cells rich in glycogen, demonstrate the restored metabolic trophism and dynamics of the whole epithelium. [Courtesy of Prof. A. Calligaro. University of Pavia, Italy]

Two Renewal Mechanisms in One

Ablation -immediately contracts & removes epidermal dyschromia/damage

Thermal effect -heating the upper dermis promotes collagen growth in the skin


This mini-invasive laser-assisted procedure is performed in a medical practice, on an outpatient or day-hospital basis; it does not involve incisions or sutures and it requires few minutes for every session.

The treatment DOES NOT usually require anaesthesia; however, if the patient prefers, an anaesthetic cream can be used.

Results can be noticed after the first session; normally we recommend a full cycle of 4-5 sessions 45-60 days apart. However, the number of sessions can change according to the level of vaginal atrophy to be treated. Only your gynaecologist can evaluate and recommend the best suited treatment plan after a careful examination.

Beneficial actions

The laser's stimulation action on collagen improves the state of the mucosa that lines the vaginal walls and promotes rehydration and functional recovery of the vaginal tissues.

Thanks to its action on factors that determine dryness, fragility and loss of mucosal elasticity, this regenerating treatment can eliminate troublesome itching, irritation and pain, which become particularly acute during intercourse. As a result, most of the treated patients report a substantial improvement in their quality of life and in their sexual life.

This stimulation and rejuvenation process involves cells and tissues and takes a few weeks to be completed. Results will be more noticeable approximately one month and a half after the end of the treatment.


Risks for patients treated with Monalisa Touch™ are minimal. Most women report temporary side effects, slight redness or swelling: some discomfort that usually disappears after one or two days of rest.

During the healing process, it may be recommended to avoid lifting weights or some activities, such as taking a hot bath, or physical exercise. Your doctor will give you specific indications for a speedy recovery.